Faktor faktor yang mempengaruhi derajat keparahan penyakit paru obstruktif kronis di Rumah Sakit Umum Siloam Karawaci

Wani, Siau (2020) Faktor faktor yang mempengaruhi derajat keparahan penyakit paru obstruktif kronis di Rumah Sakit Umum Siloam Karawaci. Bachelor thesis, Universitas Pelita Harapan.

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Abstract

Latar Belakang : Penyakit Paru Obstruktif Kronis (PPOK) merupakan penyakit kronis yang bersifat progresif dan menetap pada saluran napas akibat respons inflamasi terhadap zat-zat berbahaya yang bersifat non-reversible. Prevalensi tahun 2016 menunjukkan kasus PPOK mencapai 251 juta kasus secara global. Banyak faktor yang dapat mencetus kejadian PPOK, sehingga perlu dilakukan analisa lebih lanjut agar dapat menjauhi paparan faktor tersebut. Tujuan : Menganalisa faktor-faktor yang dapat mempengaruhi derajat keparahan PPOK. Metode : Penelitian ini menggunakan studi deskriptif analitik dengan desain potong lintang kepada 104 pasien PPOK di Rumah Sakit Umum Siloam tanpa penyakit komorbiditas dan riwayat asma atau tuberkulosis dari bulan Desember 2019-Maret 2020. Data diperoleh melalui pengisian kuesioner dan wawancara medis. Hasil : Dari 104 orang, terdapat 84 orang pria dan berhubungan dengan derajat PPOK (p value 0.013). Terdapat hubungan signifikan antara Indeks Brinkman dengan derajat PPOK (p value 0.001). Terdapat pula hubungan signifikan antara IMT dengan derajat PPOK (p value 0.031). Tidak terdapat hubungan signifikan antara pekerjaan dengan derajat PPOK (p value 0.495). Setelah dilakukan uji multivariat, hanya Indeks Brinkman yang memiliki hubungan bermakna dengan derajat PPOK yaitu p value 0.018 dan OR 3.607. Kesimpulan : Faktor yang harus dijauhi agar dapat mengurangi kejadian PPOK adalah merokok. Variabel lain seperti IMT, usia dan jenis kelamin adalah faktor perancu dari penelitian ini. / Background: Chronic Obstructive Pulmonary Disease (COPD) is a chronic, progressive, and non-reversible disease that attacks respiratory tract and caused by inflammatory response due to dangerous substances. In 2016, the prevalence of COPD reaches 251 million cases globally. Many factors triggers the incidence of COPD, therefore further analysis is required so that the exposure of the factors can be avoided. Aim: To examine the factors that may influence the severity of COPD Method: This study is a descriptive analytic study with a cross sectional study design to 104 COPD patients in Rumah Sakit Umum Siloam without comorbid diseases and history of asthma or tuberculosis from December 2019 to March 2020. Data are obtained through questionnaire and history taking. Results: From 104 respondents, 84 of them are male and the data shows that it is related with COPD severity (p value 0.013). The relation between Brinkman Index and COPD severity are also found (p value 0.001). There is a significant relation between BMI and COPD severity (p value 0.031). There are no significant relation between occupation and COPD severity (p value 0.495). After multivariate analysis conducted, only Brinkman Index that shows a significant relation towards COPD severity with p value of 0.018 and OR of 3.607. Conclusion: Factor that should be avoided to reduce the risk of COPD is smoking. Other variables such as BMI, age, and gender are confounding in this study.

Item Type: Thesis (Bachelor)
Creators:
CreatorsNIMEmail
Wani, Siau01071170030siauwani22@gmail.com
Contributors:
ContributionContributorsNIDN/NIDKEmail
Thesis advisorSiahaan, Sylvia Sagita0308118404sylvia.siahaan@uph.edu
Uncontrolled Keywords: ppok ; merokok; derajat keparahan
Subjects: R Medicine > R Medicine (General)
Divisions: University Subject > Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine
Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine
Depositing User: Siau Wani
Date Deposited: 14 Oct 2020 04:10
Last Modified: 25 Jan 2021 00:25
URI: http://repository.uph.edu/id/eprint/11224

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