Korelasi persentasi tangkapan, berat, dan volume kelenjar tiroid terhadap kadar hormon FT4 dan TSH pada pasien penyakit tiroid

Elsye, Elsye (2020) Korelasi persentasi tangkapan, berat, dan volume kelenjar tiroid terhadap kadar hormon FT4 dan TSH pada pasien penyakit tiroid. Bachelor thesis, Universitas Pelita Harapan.

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Abstract

Latar Belakang : Penyakit gangguan tiroid di Indonesia menempati posisi kedua terbanyak dalam daftar penyakit metabolik setelah penyakit diabetes mellitus. Pemeriksaan utama untuk mendiagnosis hipertiroid adalah dengan mengukur kadar T3, T4, dan TSH dalam tubuh. Sidik tiroid dapat dilakukan untuk mendapat gambaran fungsi kelenjar tiroid pada penyakit tersebut. Walaupun telah banyak dilakukan penelitian mengenai hubungan antara nilai tangkapan, berat, dan volume kelenjar tiroid dengan hormon tiroid, namun belum banyak diungkap mengenai korelasi antara fungsi kelenjar tiroid yang dinilai dengan perubahan kadar hormon tiroid dan sidik tiroid. Tujuan Penelitian: Untuk mengetahui korelasi antara persentase nilai tangkapan, volume dan berat kelenjar tiroid dari pemeriksaan sidik tiroid dengan nilai hormon tiroid FT4 dan TSH pada penderita penyakit tiroid di rumah sakit MRCC. Metode Penelitian: Penelitian ini menggunakan desain studi potong lintang. Sampel penelitian sebesar 40 subjek diambil dengan metode konsekutif purposif. Analisa statistik menggunakan uji parametrik dengan uji korelasi pearson. Hasil Analisis Data: Penelitian ini menunjukan terdapat korelasi yang bermakna antara hormon TSH dan FT4 dengan persentase tangkapan tiroid, volume tiroid, dan berat tiroid dari pemeriksaan sidik tiroid. Terdapat korelasi positif antara hormon FT4 dengan persentase tangkapan tiroid, volume, dan berat tiroid. Sedangkang hormon TSH berkorelasi negative dengan persentase tangkapan tiroid, volume, dan berat tiroid. Simpulan: Terdapat korelasi yang bermakna antara persentase tangkapan, volume, dan berat kelenjar tiroid dengan kadar hormon FT4 dan TSH pada pasien penyakit tiroid di Rumah Sakit MRCCC. Kata Kunci Sidik tiroid, kadar hormon tiroid, hipertiroid Jumlah Kata: 286 kata / Background: Thyroid disorders in Indonesia holds second place after diabetes mellitus in the list of metabolic diseases. The gold standard test of hyperthyroidism is the thyroid function test by measuring thyroid serum hormone levels. But, thyroid function test cannot give us the full information about the thyroid problems. Thyroid scintigraphy can be done to give us a better insight about the thyroid function. Even though there are many researches about the correlation between the thyroid uptake, weight, and volume with thyroid hormone, but there are only a few that explains the correlation between the thyroid function and the imaging of the thyroid gland using thyroid scintigraphy. Purpose: The purpose of this research is to determine the correlation between thyroid uptake, thyroid volume, and thyroid weight from the thyroid scintigraphy with the level of TSH and FT4 hormone for thyroid disorder patients in MRCCC hospital. Methods: This research used cross-sectional design. The minimum sample of this research is 40 samples and taken using executive purposes method. Result: The study showed significant correlation between TSH and FT4 levels with thyroid uptake, volume, and weight from the thyroid scan examination. FT4 level and thyroid uptake, volume, and weight had a positive correlation while TSH levels and thyroid uptake, volume, and weight had a negative correlation. Conclusion: There is significant relationship between uptake, volume, and weight of the thyroid gland with FT4 and TSH hormone levels in MRCCC hospital’s patients with thyroid disorder. Key Words: Thyroid Scan, hormone thyroid levels, hyperthyroid Number of Words: 287 words

Item Type: Thesis (Bachelor)
Creators:
CreatorsNIMEmail
Elsye, ElsyeNIM01071170154elsyesie99@gmail.com
Contributors:
ContributionContributorsNIDN/NIDKEmail
Thesis advisorYudistiro, RyanNIDN0315078303ryannuclear@gmail.com
Uncontrolled Keywords: sidik tiroid ; kadar hormon tiroid ; hipertiroid
Subjects: R Medicine > R Medicine (General)
Divisions: University Subject > Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine
Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine
Depositing User: Elsye Elsye
Date Deposited: 02 Nov 2020 02:16
Last Modified: 02 Nov 2020 02:16
URI: http://repository.uph.edu/id/eprint/11850

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