Perbandingan fungsi kognitif pada wanita pre menopause dan pasca menopause = Cognitive function difference between premenopausal and postmenopausal women

Damayanti, Nova (2018) Perbandingan fungsi kognitif pada wanita pre menopause dan pasca menopause = Cognitive function difference between premenopausal and postmenopausal women. Bachelor thesis, Universitas Pelita Harapan.

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Abstract

Menopause is often associated with various complaints such as memory problems, hot flushes and night sweats. Even though menopause is a change of the reproductive system, the neurological system is also involved as well. With the decline of estrogen, estrogen-regulated neurological system will be affected which results as an impact on cognitive function. Nevertheless, previous research on estrogen and cognitive function in postmenopausal women has not reach a consistent result. This study aims to determine cognitive function difference between premenopausal and postmenopausal women. This research is a numerical comparative analytic study which is conducted by cross sectional method. A sample of 98 subjects will be chosen by purposive sampling. Cognitive function will be assessed using MoCA-Ina and other data will be completed using the questionnaire. Data obtained will be processed using Microsoft Excel 2016 and SPSS. The statistical test when eligible is unpaired T Test and otherwise Mann Whitney will be used. The mean score of MoCA in premenopausal women is 26.39 ± 1.89 while the score in postmenopausal women is 22.22 ± 3.29. Result from Mann-Whitney test shows p < 0.001. This study shows that there is a significant difference between cognitive function of premenopausal and postmenopausal women / Menopause sering dikaitkan dengan berbagai keluhan seperti masalah memori, hot flush dan keringat malam. Walaupun menopause adalah suatu perubahan pada sistem reproduksi namun ternyata perubahan neurologis juga ikut berpartisipasi. Dengan turunnya estrogen, sistem neurologis yang diregulasi oleh estrogen akan terpengaruh sehingga akan berdampak pada fungsi kognitif. Meskipun begitu penelitian sebelumnya tentang estrogen dan fungsi kognitif pada wanita pasca menopause masih belum konsisten. Penelitian ini bertujuan untuk mengetahui perbedaan fungsi kognitif pada wanita pre menopause dan pasca menopause. Jenis penelitian ini adalah analitik komparatif numerik yang dilaksanakan dengan metode potong lintang. Sampel sebanyak 98 subjek akan dipilih dengan dengan cara purposive sampling. Fungsi kognitif akan diukur dengan MoCA-Ina dan data lain akan dilengkapi menggunakan kuesioner. Data yang diperoleh akan diproses menggunakan Microsoft Excel 2016 dan SPSS. Uji statistik bila memenuhi syarat adalah T test tidak berpasangan dan jika tidak akan digunakan Mann Whitney. Pada kategori pre menopause didapatkan rata-rata nilai MoCA sebesar 26.39 ± 1.89 sedangkan pada kategori pasca menopause sebesar 22.22 ± 3.29. Dari hasil uji mann whitney didapatkan p < 0.001. Dari hasil penelitian didapatkan perbedaan yang signifikan antara fungsi kognitif pada wanita pre menopause dan pasca menopause.

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