Pengaruh durasi hemodialisis terhadap depresi pada pasien penyakit ginjal kronik stadium 5 = The effect of hemodialysis duration towards depression in patients with chronic kidney disease stage 5

Permadijana, Diajeng (2018) Pengaruh durasi hemodialisis terhadap depresi pada pasien penyakit ginjal kronik stadium 5 = The effect of hemodialysis duration towards depression in patients with chronic kidney disease stage 5. Bachelor thesis, Universitas Pelita Harapan.

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Abstract

Background: Indonesian Society of Nephrology reported that there are 12.5% cases of chronic kidney disease (CKD). On CKD stage 5 kidney’s function has greatly decreases so hemodialysis is required to replace the kidney’s function, however hemodialysis duration can affect the occurrence of depression. On previous study, there was a difference in depression level with hemodialysis duration for 6 months. It has been proven that depression will occur between hemodialysis duration for 3 to 12 months with the highest incidence in 8 months. Therefore, this study will observe the effect of hemodialysis duration for 8 and 12 months towards the occurrence of depression. Aim: To find out the effect of hemodialysis duration for 8 and 12 months toward the occurrence of depression on patient with CKD stage 5. Material and Method: Thirty two patients with CKD stage 5 who met the criteria were taken as the study samples, then divided into 2 groups ie group with hemodialysis duration for 8 months and 12 months. Patient was obtained from hemodialysis center in RS Medika Dramaga, GETHealthy Klinik Hemodialisis, RSU Siloam, dan Klinik Garuda Sentra Medika. The assessment of depression level used Beck Depression Inventory questioner. Mean and standard deviation from each group was compared using Mann-Whitney U method with degree of confidence 95% (p<0.05). Result: In the group with 8 months duration of hemodialysis shows 100% mild depression. In the group with 12 months duration of hemodialysis shows 56,25% mild depression, 37,5% moderate depression, and 6,25% severe depression. Statistical analysis with Mann-Whitney U from both groups showed a significant difference (p<0,05) at all depression level. Conclusion: The hemodialysis duration in patients with stage 5 chronic kidney disease affects the severity of the depression level / Latar Belakang: Perhimpunan Nefrologi Indonesia melaporkan bahwa terdapat 12,5% penderita penyakit ginjal kronik (PGK). Pada PGK stadium 5 fungsi ginjal sudahlah sangat menurun sehingga diperlukan tindakan hemodialisis untuk menggantikan fungsi ginjal tersebut, namun durasi hemodialisis dapat mempengaruhi terjadinya depresi. Pada penelitian sebelumnya masih terdapat perbedaan tingkat depresi pada durasi hemodialisis 6 bulan. Telah dibuktikan bahwa akan terjadi depresi di antara durasi hemodialisis 3 sampai 12 bulan dengan kejadian terbanyak pada durasi 8 bulan. Oleh karena itu, pada penelitian ini akan diamati pengaruh durasi hemodialisis selama 8 dan 12 bulan terhadap terjadinya depresi. Tujuan: Mengetahui pengaruh durasi hemodialisis selama 8 dan 12 bulan terhadap terjadinya depresi pada pasien PGK stadium 5. Bahan dan Cara: Tiga puluh dua pasien PGK stadium 5 yang memenuhi kriteria diambil sebagai sampel penelitian, kemudian dibagi menjadi dua kelompok yaitu kelompok dengan durasi hemodialisis 8 bulan dan kelompok dengan durasi 12 bulan. Pasien diperoleh dari instalasi hemodialisis pada RS Medika Dramaga, GETHealthy Klinik Hemodialisis, RSU Siloam dan Klinik Garuda Sentra Medika. Penilaian tingkat depresi pada masing-masing pasien digunakan kuesioner Beck Depression Inventory. Rata-rata dan standar deviasi masing-masing kelompok dibandingkan menggunakan uji Mann-Whitney U dengan derajat kepercayaan 95% (p<0.05). Hasil: Pada kelompok yang dilakukan hemodialisis selama 8 bulan didapatkan 100% depresi ringan. Pada kelompok dengan durasi hemodialisis 12 bulan menunjukkan kejadian depresi ringan 56,25%, depresi sedang 37,5% dan depresi berat 6,25%. Analisa statistik dengan uji Mann-Whitney U dari kedua kelompok di atas menunjukkan perbedaan yang bermakna (p<0.05) pada seluruh tingkat depresi. Kesimpulan: Lamanya durasi hemodialisis pada pasien PGK stadium 5 mempengaruhi keparahan tingkat depresi.

Item Type: Thesis (Bachelor)
Creators:
CreatorsNIMEmail
Permadijana, DiajengUNSPECIFIEDUNSPECIFIED
Contributors:
ContributionContributorsNIDN/NIDKEmail
Thesis advisorAtmodjo, Wahyuni LukitaUNSPECIFIEDUNSPECIFIED
Additional Information: SK 71-15 PER p
Uncontrolled Keywords: penyakit ginjal kronik stadium 5; hemodialisis; tingkat depresi; chronic kidney disease stage 5; hemodialysis; depression level
Subjects: R Medicine > R Medicine (General)
Divisions: University Subject > Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine
Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine
Depositing User: Users 13 not found.
Date Deposited: 04 Mar 2020 06:34
Last Modified: 01 Oct 2021 07:44
URI: http://repository.uph.edu/id/eprint/8090

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