Vallencya, Vallencya (2021) Rasa pahit dan aktivitas inhibisi α-glukosidase daun sambiloto dengan penggunaan berbagai jenis adsorben = Bitterness and α-glucosidase inhibition activity of sambiloto leaves using types of adsorbents. Bachelor thesis, Universitas Pelita Harapan.
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Abstract
Daun sambiloto (Andrographis paniculata) adalah daun herbal yang banyak digunakan karena memiliki berbagai sifat fungsional, namun memiliki rasa yang sangat pahit sehingga kurang disukai. Tujuan dalam penelitian ini adalah untuk mengetahui pengaruh adsorben dan waktu pendidihan terhadap intensitas rasa pahit, senyawa fitokimia, dan aktivitas inhibisi α-glukosidase daun sambiloto. Adsorben yang digunakan adalah bentonit, diatomit, dan attapulgit aktif dengan waktu pendidihan 5, 10, dan 20 menit. Daun yang telah diberi pelakuan kemudian dianalisis sensori (intensitas rasa pahit), total fenolik, total flavonoid, dan aktivitas inhibisi α-glukosidase. Hasil menunjukkan perlakuan attapulgit aktif dengan waktu pemasakan 20 menit mampu mengurangi intensitas rasa pahit paling besar, diikuti bentonit dan diatomit. Sedangkan bentonit dengan waktu pendidihan 20 menit mampu mengurangi aktivitas inhibisi α-glukosidase paling besar, diikuti attapulgit aktif dan diatomit. Berkurangnya intensitas rasa pahit mempengaruhi pengurangan senyawa fitokimia (total fenolik dan total flavonoid), dan aktivitas inhibisi α-glukosidase karena adanya korelasi. Perlakuan attapulgit aktif dengan waktu pendidihan 20 menit merupakan perlakuan terbaik karena mampu mengurangi intensitas rasa pahit hingga 56% dan mempertahankan aktivitas inhibisi α-glukosidase pada IC50 711,455 ppm. / Green chiretta (Andrographis paniculata) leaves is a medicinal herb that widely used due to its functional properties, but have a very bitter taste thus it is less liked. The aim of this study was to know the effect of different types of adsorbents and boiling time towards bitterness intensity, phytochemical compounds, and α-glucosidase inhibition activity. The adsorbent used were bentonite, diatomite, and activated attapulgite with boiling time. Treated leaves then analyzed for its sensory (bitterness intensity), total phenolic, total flavonoid, and α-glucosidase inhibition activity. The results showed the treatment of activated attapulgite with 20 minutes of boiling time was able to reduce bitterness intensity the most, followed by bentonite and diatomite respectively. While bentonite with 20 minutes of boiling time was able to reduce α-glucosidase inhibition activity the most, followed by activated attapulgite and diatomite respectively. The reduced bitterness intensity affects the reduction of phytochemical compounds (total phenolic and total flavonoid) and α-glucosidase inhibition activity because of their correlation. The treatment of activated attapulgite with 20 minutes of boiling time was the best treatment because it can reduce bitterness intensity to 56% and maintain the α-glucosidase inhibition activity with IC50 711,455 ppm.
Item Type: | Thesis (Bachelor) | ||||||||
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Uncontrolled Keywords: | daun sambiloto; adsorben; bentonit; diatomit; attapulgit; aktivitas antidiabetes; α-glukosidase | ||||||||
Subjects: | T Technology > TP Chemical technology > TP368-456 Food processing and manufacture | ||||||||
Divisions: | University Subject > Current > Faculty/School - UPH Karawaci > Faculty of Science and Technology > Food Technology Current > Faculty/School - UPH Karawaci > Faculty of Science and Technology > Food Technology |
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Depositing User: | Users 6804 not found. | ||||||||
Date Deposited: | 17 Feb 2021 01:10 | ||||||||
Last Modified: | 17 Feb 2021 01:10 | ||||||||
URI: | http://repository.uph.edu/id/eprint/19744 |
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