Background: Shame has a very detrimental influence in students’ learning process. There are 4 responses in dealing with shame, namely avoidance, self attack, withdrawal, and attack others. However, there is not much data on how nursing students respond to shame, specifically in Indonesia. Aim: To the describe shame responses of nursing students, based on the situations in clinical setting at one private university in Indonesia. Research Method: This was a descriptive quantitative method using accidental sampling technique. The instrument used was the Indonesian version of Compass of Shame Scale (CoSS) version 5 that was valid and reliable for shame response ( Cronbach= 0,928) and situations in clinical setting ( Cronbach= 0,958). This study obtained 282 people and data was analyzed using descriptive statistical procedures. Result: The shame response that often occurred were avoidance (Mean= 2.74) and attack self (Mean= 2.63) compared to withdrawal (Mean= 2.47) and attack other (Mean= 2.21). While shame experience that often happened in clinical settings were a situation where someone experienced rejection by another person (Mean= 2.80) and a situation where someone made a mistake in public (Mean= 2.80). Recommendation: Further study is to be conducted to explore nursing students’ shame experiences and factors contributing to shame responses.