This study aims to understand the relationship between the perceived usefulness, ease of use and security of Asian Millennials towards e-commerce and their purchase intention of online residential real estate. A quantitative data collection method was used through the distribution of online questionnaires via Google form and Asian Millennials who currently reside and were born between the years (Born 1981-1996) were selected as the respondents of this study. The online questionnaire collected a total of 210 respondents, of which 80 did not meet the requirements of this study and were filtered out. Hence, 130 responses were collected as the study sample. A Technology Acceptance Model (TAM) framework was adopted for the purposes and context of this research topic. The statistics software platform IBM’s SPSS Version 26.0.1 was selected for analysis of data to compute values used for descriptive statistics,validity and reliability tests, multicollinearity, coefficient of determination values,T-statistics values, and P-values for hypothesis testing. Overall, the results of this study showed that 2 out of 3 of the research hypotheses were both significant and supported; namely Hypothesis 2 (H2) and Hypothesis 3 (H3). Overall, this study concluded that no positive relationship exists between perceived usefulness (X1) and purchase intention (Y) but there is a positive relationship between perceived ease of use (X2) and purchase intention (Y), and between perceived security (X3) and purchase intention (Y).