Financial statement is a crucial tool in conveying a company’s financial information, which will help users during decision-making process, based on their assessment of the company’s financial performance. However, Pernyataan Standar Akuntasi Keuangan (PSAK) 25 allows management the discretion to choose the accounting methods adopted, which can be misused by opportunistic managers to manage earnings for their own benefits. Not only the level of earnings management differs between different companies, but also between different periods of the same company. This research aims to study the influence of profitability, leverage, board independence, firm size and information asymmetry towards the earnings management.Earnings management is a purposeful intervention within the constraints of generally accepted accounting principles to achieve desired level earnings. Managing earnings to maximize shareholders’ values represents efficient earnings management, while managing earnings to fulfill managers’ desirable goals represents opportunistic earnings management.The research objects used in this study are LQ45 index companies that were listed consecutively during 2013-2017 periods. This study is a descriptive study conducted under quantitative approach using secondary data in the form of financial statements. The sampling method used is purposive sampling method, with a total sample of 21 companies from a population of 69 Indonesian publicly listed in LQ45 index companies. The study uses multiple linear regression model in the analysis. The result of this study indicates that profitability and board independence have a significant positive influence, while firm size has a significant negative influence on earnings management partially. Meanwhile, leverage has an insignificant negative influence and information asymmetry has an insignificant positive influence on earnings management partially. Simultaneously, those five independent variables have a significant influence on earnings management