Laboratorium kimia sebagai salah satu fasilitas pendukung perkuliahan diharapkan dapat memberi kenyamanan dan keselamatan bagi para penggunanya. Pendekatan ergonomis di dalam perancangan laboratorium kimia merupakan satu hal yang penting untuk diperhatikan. Terkait pengembangan laboratorium, Laboratorium Kimia Jurusan Teknik Industri UPH Surabaya akan menambahkan beberapa fasilitas kerja guna mendukung aktivitas di laboratorium, yaitu lemari asam dan shower. Perancangan fasilitas kerja tersebut menggunakan analisis antropometri, material, teknik, estetika, dan fungsional agar didapatkan fasilitas kerja yang ergonomis, nyaman dan aman bagi penggunanya. Pada penelitian ini, perancangan tata letak menggunakan metode Systematic Layout Planning (SLP). Dari hasil analisis didapatkan dimensi lemari asam 120 cm x 80 cm x 240 cm, dengan tinggi meja 95 cm, tinggi jendela 175 cm, panjang lemari 80 cm, bibir meja 10 cm, dan jarak lantai ke pintu lemari bawah 10 cm. Dimensi shower room 150 cm x 150 cm x 195 cm, dengan tinggi shower 185 cm, tinggi kran shower 90 cm, tinggi eye washer 90 cm, tinggi handheld shower 90 cm, panjang shower 50 cm, tinggi pintu 180 cm, dan lebar pintu 80 cm. Tata letak usulan tidak mengubah posisi meja laboratorium seperti pada layout awal, namun menetapkan tempat-tempat yang tepat untuk fasilitas baru berdasarkan kepentingan kedekatan dan faktor keselamatan dan keamanan dalam laboratorium. Pada penelitian ini juga dirancang prosedur operasi standar (SOP) untuk mendukung sistem kerja dari fasilitas, yaitu SOP Penggunaan Laboratorium Kimia, SOP Pelaksanaan Praktikum dengan Lemari Asam, dan SOP Penggunaan Shower Room / Chemical laboratory as one of study facilities is expected to give comfort and safety for its users. Ergonomic approach in a chemical laboratory design is an important thing to be considered. Related to the development of the laboratory, the Chemical Laboratory of Industrial Engineering of Universitas Pelita Harapan Surabaya will add some working facilities to support the activities in the laboratory, those are fume hood and shower. The working facilities design used anthropometric, material, techniques, aesthetics, and functional analysis in order to have ergonomic working facilities, comfortable and safe for the users. In this research, the layout design used Systematic Layout Planning (SLP) method. The result of fume hood dimension was 120 cm x 80 cm x 240 cm, with 95 cm of table height, 175 cm of window height, 80 cm of cabinet length, 10 cm of table edge, and 10 cm of floor to the cabinet door distance. Shower room dimension was 150 cm x 150 cm x 195 cm, with 185 cm of shower height, 90 cm of faucet height, 90 cm of eye washer height, 90 cm of handheld shower height, 50 cm of shower length, and 80 cm of door width. The proposed layout did not alter the position of laboratory tables as in the initial layout, but only set the right places for the new facilities based on closeness importance, safety and security factors in laboratory. In this research, several standard operating procedures (SOP) were designed to support working systems of the facilities such as SOP of the Use of Chemical Laboratory, SOP of Practice with Fume Hood, and SOP of the Use of Shower Room