ABSTRAK Pengaruh Tingkat Stres Akibat Pembelajaran Online terhadap Kejadian Tension Type Headache pada Mahasiswa Praklinik Fakultas Kedokteran Universitas Pelita Harapan Latar Belakang Tension type headache merupakan nyeri kepala primer yang dapat disebabkan oleh tingkat stres, serta sering terjadi pada remaja. Akibat adanya pandemi COVID-19 dapat memicu terjadinya peningkatan stres, karena perubahan metode pembelajaran menjadi online. Peningkatan tingkat stres πakibat pembelajaran online dapat memicu kejadian tension type headache. Tujuan Penelitian Mengetahui pengaruh tingkat stres akibat pembelajaran online terhadap kejadian tension type headache pada mahasiswa praklinik Fakultas Kedokteran Universitas Pelita Harapan. Hipotesis Terdapat hubungan antara tingkat stres akibat pembelajaran online terhadap kejadian tension type headache. Metode Penelitian Menggunakan penelitian analitik dengan desain studi potong lintang. Sampel diambil secara simple random sampling pada mahasiswa praklinik berjumlah 112 sampel, melalui kuesioner Headache Screening Questionnaire- Dutch Version untuk tension type headache dan Depression Anxiety Stress Scale 42 untuk tingkat stres. Hasil penelitian dianalisis menggunakan uji statistik Chi Square. Hasil Penelitian Terdapat hubungan yang signifikan antara tingkat stres akibat pembelajaran online dengan kejadian tension type headache pada mahasiswa praklinik Fakultas Kedokteran Universitas Pelita Harapan dengan nilai (p = 0,026<0,05). Kata kunci: Tension type headache, tingkat stres, mahasiswa, pembelajaran online/ ABSTRACT The Effect of Stress Levels Due to Online Learning on Tension Type Headache Incidents in Preclinical Students Faculty of Medicine, Pelita Harapan University Background Tension type headache is a primary headache that can be caused by stress levels, and often occurs in adolescents. Due to the COVID-19 pandemic, it can trigger an increase in stress, due to changes in learning methods to online. Stress levels due to online learning can trigger tension type headaches. Aim Knowing the effect of stress levels due to online learning on the incidence of tension type headache in pre-clinical students of the Faculty of Medicine, Pelita Harapan University. Hypothesis There is a relationship between stress levels due to online learning with the incidence of tension type headache. Methods Using analytical research with a cross-sectional study design. Samples were taken by simple random sampling of 112 pre-clinical students, through Headache Screening Questionnaire-Dutch Version questionnaires for tension type headache and Depression Anxiety Stress Scale 42 for stress levels. The results of the study were analyzed using Chi Square statistical test. Research result There is a significant relationship between stress levels due to online learning and the incidence of tension type headache in pre-clinical students of the Faculty of Medicine, Pelita Harapan University with a value (p = 0.026 <0.05). Keywords: Tension type headache, stress level, medical students, online learning