Penelitian ini dilakukan untuk menganalisa anteseden dari missed nursing care yang terdiri dari nurse practice environment, job satisfaction, job burnout, patient safety culture dan nurse teamwork. Penelitian ini adalah penelitian kuantitatif dengan desain studi potong lintang. Model penelitian yang digunakan dalam penelitian ini merupakan modifikasi dari penelitian-penelitian terdahulu yang kemudian diuji pada populasi perawat rawat inap di rumah sakit X di Kota Kupang. Pengambilan sampel dilakukan dengan metode sampel jenuh dengan total responden sebanyak 128 responden. Penelitian ini menggunakan metode analisa PLS-SEM. Hasil yang didapatkan adalah nurse practice environment, job satisfaction, patient safety culture dan nurse teamwork memiliki pengaruh negatif terhadap missed nursing care. Sebaliknya job burnout memiliki pengaruh positif terhadap missed nursing care. Job satisfaction memediasi hubungan antara nurse practice environment dan missed nursing care, dan hubungan antara nurse teamwork dan missed nursing care. Job burnout merupakan variabel yang paling berpengaruh terhadap missed nursing care./This study was conducted to determine the antecedents of missed nursing care which consists of nurse practice environment, job satisfaction, job burnout, patient safety culture dan nurse teamwork. This research is a quantitative study with cross-sectional design. This research model was modified from previous study which then tested to inpatient nurses at hospital X at Kupang. Saturated sampling was done with a total of 128 respondents. This study was analyzed using PLS-SEM. The results of this study are nurse practice environment, job satisfaction, patient safety culture and nurse teamwork have an inverse relationship with missed nursing care. On the other hand, job burnout has a positive relationship with missed nursing care. In addition, we found that job satisfaction mediates the negative relationship between nurse practice environment and nurse teamwork with missed nursing care. Job burnout has the most impact to missed nursing care.