In today’s world, it is not enough for students to just learn from a single track learning. Moreover it is even more important for students as well as teachers to tackle issue they learn in the classroom from various points of views, one way is through an interdisciplinary learning approach. In order for teachers to be competent in applying interdisciplinary learning, the right type of leadership needs to guide these teachers. Besides the right type of leadership, teachers can not tackle a particular issue on their own, there needs to be a collaboration among the teachers. The purpose of this quantitative study is to analyse the influence of transformational leadership and teacher collaboration on teachers’ ability in implementing interdisciplinary learning at XYZ Schools. Fourty seven teachers at XYZ Schools completed the online questionnaires. The path analysis through PLS SEM method was employed to test the proposed hypothesis. The results showed that transformational leadership has a positive influence on teachers’ ability in implementing interdisciplinary learning. Added to that, teacher collaboration has a positive influence on teachers’ ability in implementing interdisciplinary learning. Also, transformational leadership has a positive influence on teacher collaboration. / Di dunia sekarang ini, siswa tidak cukup hanya belajar dari pembelajaran satu jalur saja. Terlebih lagi, penting bagi siswa dan juga guru untuk mengatasi permasalahan yang mereka pelajari di kelas dari berbagai sudut pandang, salah satu caranya adalah melalui pendekatan pembelajaran interdisipliner. Agar guru kompeten dalam menerapkan pembelajaran interdisipliner, maka perlu adanya model kepemimpinan yang tepat dalam membimbing guru tersebut. Selain model kepemimpinan yang tepat, guru tidak bisa menangani suatu permasalahan sendirian, perlu adanya kolaborasi antar guru. Tujuan penelitian kuantitatif ini adalah untuk menganalisis pengaruh kepemimpinan transformasional dan kolaborasi guru terhadap kemampuan guru dalam melaksanakan pembelajaran interdisipliner di sekolah XYZ. Empat puluh tujuh guru di sekolah XYZ menyelesaikan kuesioner online. Analisis jalur melalui metode PLS SEM digunakan untuk menguji hipotesis yang diajukan. Hasil penelitian menunjukkan bahwa kepemimpinan transformasional mempunyai pengaruh positif terhadap kemampuan guru dalam melaksanakan pembelajaran interdisipliner. Selain itu, kolaborasi guru memberikan pengaruh positif terhadap kemampuan guru dalam melaksanakan pembelajaran interdisipliner. Selain itu, kepemimpinan transformasional mempunyai pengaruh positif terhadap kolaborasi guru.