Penelitian ini bertujuan untuk mengetahui pengaruh knowledge management, talent management, serta employee development terhadap employee performance, kemudian untuk mengetahui pengaruh knowledge management dan talent management terhadap employee development, serta untuk mengetahui pengaruh knowledge management dan talent management terhadap employee performance dengan mediasi employee development. Penelitian ini merupakan penelitian kuantitatif dan dalam analisis statistik menggunakan PLS-SEM melalui software SmartPLS 4. Data dikumpulkan dengan menyebarkan kuesioner. Dalam penentuan sampel, digunakan teknik non-probability sampling dengan jenis purposive yaitu staf administrasi dari RSUP Dr. Wahidin Sudirohusodo Makassar sebanyak 125 responden. Hasil penelitian menunjukkan talent management berpengaruh terdahap employee development, employee development memediasi hubungan antara talent management dengan employee performance, dan employee development berpengaruh terdahap employee performance. Sementara itu hipotesis lainnya menunjukkan bahwa knowledge management tidak berpengaruh terdahap employee performance, talent management tidak berpengaruh terdahap employee performance, knowledge management tidak berpengaruh terdahap employee development, dan employee development tidak memediasi hubungan antara knowledge management dengan employee performance. / This research aims to determine the influence of knowledge management, talent management and employee development on employee performance, then to determine the influence of knowledge management and talent management on employee development, and to determine the influence of knowledge management and talent management on employee performance through the mediation of employee development. This research is a quantitative research and the statistical analysis used is PLS-SEM via SmartPLS 4 software. Data was collected by distributing questionnaires. In determining the sample, a non-probability sampling technique was used with a purposive type, namely administrative staff from RSUP Dr. Wahidin Sudirohusodo Makassar as much as 125 respondents. The research results shows that talent management has an effect on employee development, employee development mediates the relationship between talent management and employee performance, and employee development has an effect on employee performance. Meanwhile, other hypotheses shows that knowledge management has no effect on employee performance, talent management has no effect on employee performance, knowledge management has no effect on employee development, and employee development does not mediate the relationship between knowledge management and employee performance.