Widarso, Eldwin (2024) Penurunan derajat spastisitas pasien pascastroke dalam durasi dua minggu setelah injeksi dosis rendah bont-a di Siloam Hospitals Lippo Village Gedung B. Bachelor thesis, Universitas Pelita Harapan.
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Abstract
Latar Belakang: Stroke adalah defisit neurologis fokal yang terjadi akibat kerusakan sistem saraf pusat. Salah satu komplikasi umum setelah stroke adalah spastisitas, kondisi di mana otot-otot menjadi kaku, tegang, dan sulit dikendalikan. Pengobatan efektif untuk spastisitas adalah toksin botulinum. Penelitian ini bertujuan untuk mengamati penurunan derajat spastisitas dalam dua minggu setelah injeksi toksin botulinum dengan dosis rendah serta membandingkannya dengan penelitian dosis tinggi. Tujuan: Untuk mengetahui apakah injeksi dosis rendah toksin botulinum menurunkan derajat spastisitas pasien pascastroke dalam durasi dua minggu setelah injeksi. Metode: Penelitian ini merupakan studi deskriptif numerik dengan metode longitudinal prospektif. Data primer dikumpulkan melalui wawancara dan pemeriksaan fisik pasien spastisitas pascastroke di Siloam Hospitals Lippo Village Gedung B. Hasil: Dari 30 pasien yang memenuhi kriteria, semuanya menerima 10 unit toksin botulinum. Hasil penelitian menunjukkan bahwa skala MAS menurun sebesar 1 hingga 2 skala dengan rata rata penurunan 1,53. Penelitian dengan dosis tinggi menunjukkan hasil yang sebanding yang dilaporkan pada 4 hingga 6 minggu setelah suntik. Kesimpulan: Injeksi dosis rendah toksin botulinum menurunkan derajat spastisitas pasien pascastroke dalam durasi dua minggu setelah injeksi di Siloam Hospitals Lippo Village Gedung B. Kata Kunci: Spastisitas pascastroke, Toksin botulinum, Derajat spastisitas, Dosis rendah Referensi: 46 (1996-2023) / Background: Stroke is a focal neurological deficit caused by damage to the central nervous system. One common complication following a stroke is spasticity, where the muscles become stiff, tense, and difficult to control. Botulinum toxin is an effective treatment for spasticity. This study aims to observe the reduction in spasticity within two weeks after a low dose injection of botulinum toxin and compare the results with higher doses studies. Objective: To find out whether low dose injection of botulinum toxin reduces the degree of spasticity in post-stroke patients within two weeks after injection. Methods: This is numerical descriptive study with prospective longitudinal methods. Primary data was collected through interviews and physical examination of post-stroke spasticity patients at Siloam Hospitals Lippo Village Building B. Results: Of the 30 patients met the criteria, all received 10 units of botulinum toxin. The research results showed that the MAS scale decreased by 1 to 2 scales with an average decrease of 1.53. High-dose studies show comparable results reported at 4 to 6 weeks after injection. Conclusion: Low dose injection of botulinum toxin reduces the degree of spasticity in post-stroke patients within two weeks after injection at Siloam Hospitals Lippo Village Building B. Keywords: Post-stroke spasticity, Botulinum toxin, Degree of spasticity, Low dose References: 46 (1996-2023)
Item Type: | Thesis (Bachelor) |
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Creators: | Creators NIM Email ORCID Widarso, Eldwin NIM01071210162 eldwin910@gmail.com UNSPECIFIED |
Contributors: | Contribution Contributors NIDN/NIDK Email Thesis advisor Siahaan, Yusak Mangara Tua NIDN20040134 yusak.siahaan@lecturer.uph.edu |
Uncontrolled Keywords: | spastisitas pascastroke; toksin botulinum; derajat spastisitas; dosis rendah |
Subjects: | R Medicine > R Medicine (General) |
Divisions: | University Subject > Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine |
Depositing User: | EDUARDUS ELDWIN WIDARSO |
Date Deposited: | 29 Oct 2024 03:38 |
Last Modified: | 29 Oct 2024 03:42 |
URI: | http://repository.uph.edu/id/eprint/65507 |