Tujuan dari penelitian ini adalah untuk mengetahui pengaruh dari ICT demands, ICT resources, work-family balance, dan burnout terhadap job satisfaction. Dalam penelitian ini, metode cross-sectional digunakan untuk mendapatkan data kuantitatif melalui kuesioner online. Teknik pengambilan menggunakan teknik non probabilitas dengan menggunakan purposive sampling kepada 160 karyawan yang telah bekerja pada PT XYZ selama 1 tahun lebih dan merupakan karyawan tetap. Teknik analisis data menggunakan perangkat lunak PLS-SEM. Hasil penelitian menunjukkan bahwa 1) ICT demands berpengaruh negatif terhadap work-family balance; 2) ICT resources berpengaruh positif terhadap work-family balance; 3) ICT demands berpengaruh positif terhadap burnout; 4) ICT resources berpengaruh negatif burnout; 5) Work-family balance berpengaruh negatif terhadap burnout; 6) Burnout berpengaruh negatif terhadap job satisfaction; 7) Work-Family Balance tidak memediasi pengaruh ICT demans terhadap Burnout; 8) Work-Family Balance memediasi pengaruh ICT resources terhadap Burnout. Hasil penelitian ini dapat memberikan implikasi manajerial yang akan membantu PT XYZ dalam meningkatkan job satisfaction./ The purpose of this study is to determine the effect of ICT demands, ICT resources, work-family balance, and burnout on job satisfaction. In this study, a cross-sectional method was used to obtain quantitative data through an online questionnaire. The sampling technique uses non-probability techniques using purposive sampling to 160 employees who have worked at PT XYZ for more than 1 year and are permanent employees. Data analysis techniques using PLS-SEM software. The results showed that 1) ICT demands have a negative effect on work-family balance; 2) ICT resources have a positive effect on work-family balance; 3) ICT demands have a positive effect on burnout; 4) ICT resources have a negative effect on burnout; 5) Work-family balance has a negative effect on burnout; 6) Burnout has a negative effect on job satisfaction; 7) ICT demands do not mediate work-family balance. Work-Family Balance does not mediate the effect of ICT demands on Burnout; 8) Work-Family Balance mediates the effect of ICT resources on Burnout. The results of this study can provide managerial implications that will help PT XYZ in increasing job satisfaction.