Ciany, Novelia (2024) Hubungan Tingkat Keparahan Obstructive Sleep Apnea dengan Kejadian Aterosklerosis di Rumah Sakit Siloam Lippo Village Gedung B. Bachelor thesis, Universitas Pelita Harapan.
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Abstract
Apnea tidur obstruktif (OSA) yang tidak diobati dikenal sebagai faktor risiko morbiditas dan mortalitas dari penyakit kardiovaskular. Angka kejadian OSA di Indonesia saat ini sebesar 31,6%. Banyak elemen kejadian patologis kompleks yang menyebabkan penyakit pembuluh darah aterosklerotik pada OSA. Ini termasuk peningkatan stres oksidatif akibat hipoksia intermiten, peradangan pada pembuluh darah, disfungsi endotel, dan akhirnya pembentukan trombosit. Aterosklerosis berhubungan erat dengan penyakit kardiovaskuler yang menyebabkan peningkatan mortalitas dan morbiditas di masyarakat. Penelitian ini bertujuan untuk mengetahui ada atau tidaknya hubungan OSA dengan kejadian aterosklerosis di Rumah Sakit Siloam Lippo Village./Untreated obstructive sleep apnea (OSA) is a known risk factor for morbidity and mortality from cardiovascular disease. The incidence of OSA in Indonesia is currently 31.6%. There are many complex pathological elements that cause atherosclerotic vascular disease in OSA. These include increased oxidative stress due to intermittent hypoxia, inflammation of the blood vessels, endothelial dysfunction, and platelet formation. Atherosclerosis is closely related to cardiovascular disease which causes increased mortality and morbidity in society. This study aims to determine whether there is a relationship between OSA and the incidence of atherosclerosis at Siloam Lippo Village Hospital Building B.
Item Type: | Thesis (Bachelor) |
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Creators: | Creators NIM Email ORCID Ciany, Novelia NIM01071210278 noveliaciany@gmail.com UNSPECIFIED |
Contributors: | Contribution Contributors NIDN/NIDK Email Thesis advisor Rivami, Dwi NIDN0314077601 dwi.rivami@uph.edu |
Uncontrolled Keywords: | Apnea Tidur Obstuktif;Aterosklerosis |
Subjects: | R Medicine > R Medicine (General) |
Divisions: | University Subject > Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine |
Depositing User: | NOVELIA CIANY |
Date Deposited: | 17 Jan 2025 02:25 |
Last Modified: | 17 Jan 2025 02:25 |
URI: | http://repository.uph.edu/id/eprint/66464 |