Latar belakang: Kanker serviks terjadi akibat pertumbuhan sel abnormal pada serviks, yang sebagian besar disebabkan oleh infeksi Human Papillomavirus (HPV). Indonesia menempati peringkat ketiga kasus kanker serviks tertinggi di dunia setelah China dan India, dengan jumlah kasus mencapai 36.964. Data dari Kementerian Kesehatan (2023) menunjukkan bahwa hanya 8,3% perempuan usia 30–50 tahun yang telah menjalani deteksi dini kanker serviks. Di wilayah kerja Puskesmas Curug, Tangerang, dari 19.448 wanita usia subur, hanya 1.338 yang telah melakukan pemeriksaan IVA. Tujuan penelitian : Mengetahui hubungan tingkat pengetahuan kanker serviks terhadap sikap wanita usia subur tentang pemeriksaan IVA di wilayah kerja Puskesmas Curug. Metode penelitian: Penelitian menggunakan pendekatan kuantitatif dengan desain cross-sectional dan teknik purposive sampling, melibatkan 392 responden wanita usia 30–49 tahun. Instrumen yang digunakan berupa kuesioner, dan analisis data dilakukan secara univariat dan bivariat dengan uji chi-square. Hasil penelitian: Hasil penelitian menunjukkan adanya hubungan signifikan antara tingkat pengetahuan dan sikap terhadap pemeriksaan IVA (p = 0,000). Saran: Diharapkan wanita usia subur meningkatkan kesadaran akan pentingnya deteksi dini kanker serviks melalui pemeriksaan IVA secara berkala yang sederhana, aman, dan mudah diakses. Selain itu, wanita disarankan untuk tidak merasa takut atau malu menjalani pemeriksaan serta aktif mencari informasi yang akurat / Background: Cervical cancer occurs due to the growth of abnormal cells in the cervix, most of which are caused by Human Papillomavirus (HPV) infection. Indonesia ranks third in the world for the highest number of cervical cancer cases after China and India, with a total of 36,964 cases. Data from the Ministry of Health (2023) show that only 8.3% of women aged 30–50 years have undergone early detection for cervical cancer. In the working area of Curug Public Health Center, Tangerang, out of 19,448 women of reproductive age, only 1,338 have undergone the Visual Inspection with Acetic Acid (VIA) test. Research Objective: To determine the relationship between the level of knowledge about cervical cancer and the attitudes of women of reproductive age regarding VIA screening in the working area of Curug Public Health Center. Research Method: This study used a quantitative approach with a cross-sectional design and purposive sampling technique, involving 392 women aged 30–49 years. The instrument used was a questionnaire, and data analysis was conducted using univariate and bivariate methods with the chi-square test. Results: The results showed a significant relationship between the level of knowledge and attitudes toward VIA screening (p = 0.000). Recommendation: Women of reproductive age are encouraged to increase their awareness of the importance of early detection of cervical cancer through regular VIA screening, which is simple, safe, and accessible at nearby health facilities. Furthermore, women are advised not to feel afraid or embarrassed to undergo the screening and to actively seek accurate information regarding the procedure.