Tuberkulosis paru masih menjadi masalah kesehatan global, termasuk di Indonesia yang menempati peringkat kedua tertinggi. Di wilayah kerja Puskesmas Binong, kasus terus meningkat. Penelitian ini bertujuan mengetahui hubungan antara tingkat pengetahuan dan sikap dengan perilaku pencegahan tuberkulosis paru. Metode yang digunakan adalah kuantitatif analitik korelatif dengan pendekatan cross-sectional. Populasi penelitian adalah seluruh masyarakat di Kelurahan Binong 36.722 orang, dengan sampel 396 responden yang dipilih secara purposive sampling. Uji statistik menggunakan spearman rho. Hasil menunjukkan sebagian besar responden memiliki pengetahuan baik 62,9% dan sikap positif 75%, namun perilaku pencegahannya masih rendah 51%). Adanya hubungan signifikan antara pengetahuan dan perilaku (p = 0,000; r = 0,251), serta sikap dan perilaku (p = 0,000; r = -0,283), meskipun arah hubungannya tidak sejalan. Kesimpulannya, sebagian besar masyarakat di wilayah kerja Puskesmas Binong memiliki pengetahuan dan sikap yang baik tentang pencegahan tuberkulosis paru, namun perilaku pencegahannya masih rendah. Terdapat hubungan signifikan antara pengetahuan dan perilaku serta antara sikap dan perilaku, meskipun arah hubungannya tidak sejalan. Disarankan agar masyarakat meningkatkan konsistensi dalam pencegahan, institusi kesehatan memperkuat edukasi praktis dengan melibatkan tokoh masyarakat, dan peneliti selanjutnya meneliti faktor lain dengan pendekatan kualitatif./Pulmonary tuberculosis is still a global health problem, including in Indonesia where it ranks second highest. In the Binong Health Center working area, cases continue to increase. This study aims to determine the relationship between the level of knowledge and attitude with the behavior of preventing pulmonary tuberculosis. The method used was quantitative correlative analytic with a cross-sectional approach. The study population was all 36,722 people in Binong Village, with a sample of 396 respondents selected by purposive sampling. Statistical test using spearman rho. The results showed that most respondents had good knowledge 62.9% and a positive attitude 75%, but their prevention behavior was still low 51%). There was a significant relationship between knowledge and behavior (p = 0.000; r = 0.251), as well as attitude and behavior (p = 0.000; r = -0.283), although the direction of the relationship was not in line. In conclusion, most people in the Binong Puskesmas working area have good knowledge and attitudes about preventing pulmonary tuberculosis, but their prevention behavior is still low. There is a significant relationship between knowledge and behavior and between attitude and behavior, although the direction of the relationship is not in line. It is recommended that the community increase consistency in prevention, health institutions strengthen practical education by involving community leaders, and further researchers examine other factors with a qualitative approach.