Optimasi formulasi dan penentuan nilai spf (sun protection factor) pada sediaan lip gloss ekstrak etanol 96% umbi bit merah (beta vulgaris l.)

Anastasya, Aura (2025) Optimasi formulasi dan penentuan nilai spf (sun protection factor) pada sediaan lip gloss ekstrak etanol 96% umbi bit merah (beta vulgaris l.). Diploma thesis, Universitas Pelita Harapan.

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Abstract

Bibir merupakan bagian tubuh yang sensitif karena tidak memiliki perlindungan alami terhadap sinar ultraviolet (UV), sehingga rentan mengalami kerusakan seperti pecah-pecah dan hiperpigmentasi. Penelitian ini bertujuan untuk mengetahui nilai Sun Protection Factor (SPF) ekstrak etanol 96% umbi bit merah (Beta vulgaris L.) serta mengevaluasi mutu fisik dan proteksi UV dari sediaan lip gloss yang diformulasikan dengan ekstrak tersebut. Ekstrak diperoleh melalui metode maserasi, dan skrining fitokimia menunjukkan adanya senyawa aktif seperti flavonoid, fenol, tanin, saponin, dan triterpenoid yang berperan dalam aktivitas tabir surya. Nilai SPF ekstrak meningkat seiring kenaikan konsentrasi: 6,73 (1000 ppm), 12,03 (2500 ppm), 21,94 (5000 ppm), 31,90 (7500 ppm), dan 36,76 (10.000 ppm). Dari tiga basis lip gloss yang dioptimasi, hanya basis B3 memenuhi syarat mutu fisik, sehingga digunakan dalam formulasi F1 (0,75%), F2 (1%), F3 (2,5%), dan F4 (5%). F1 dieliminasi karena tidak memenuhi syarat uji daya sebar, sedangkan F2, F3, dan F4 memenuhi syarat uji daya sebar serta masing-masing memiliki nilai SPF 24,73; 27,89; dan 35,20. Berdasarkan mutu fisik dan nilai SPF tertinggi, F4 ditetapkan sebagai formula terbaik. Uji stabilitas dengan cycling test selama enam siklus menunjukkan penurunan nilai SPF yang bermakna secara statistik pada F4, dari 34,70±0,099 menjadi 33,87±0,046 (p < 0,05)./Lips are a sensitive part of the body because they do not have natural protection against ultraviolet (UV) rays, so they are prone to damage such as chapping and hyperpigmentation. This study aims to determine the Sun Protection Factor (SPF) value of 96% ethanol extract of red beet tuber (Beta vulgaris L.) and evaluate the physical quality and UV protection of lip gloss preparations formulated with the extract. The extract was obtained through maceration method, and phytochemical screening showed the presence of active compounds such as flavonoids, phenols, tannins, saponins, and triterpenoids that play a role in sunscreen activity. The SPF value of the extract increased as the concentration increased: 6.73 (1000 ppm), 12.03 (2500 ppm), 21.94 (5000 ppm), 31.90 (7500 ppm), and 36.76 (10,000 ppm). Of the three lip gloss bases optimized, only base B3 met the physical quality requirements, so it was used in formulations F1 (0.75%), F2 (1%), F3 (2.5%), and F4 (5%). F1 was eliminated because it did not meet the requirements of the spreadability test, while F2, F3, and F4 met the requirements of the spreadability test and had SPF values of 24.73; 27.89; and 35.20, respectively. Based on the physical quality and the highest SPF value, F4 was determined as the best formula. Stability test with cycling test for six cycles showed a statistically significant decrease in SPF value in F4, from 34.70±0.099 to 33.87±0.046 (p < 0.05).
Item Type: Thesis (Diploma)
Creators:
Creators
NIM
Email
ORCID
Anastasya, Aura
NIM01174220013
auraanastasya264@gmail.com
UNSPECIFIED
Contributors:
Contribution
Contributors
NIDN/NIDK
Email
Thesis advisor
Trisina, Jessica
0303108505
UNSPECIFIED
Thesis advisor
Karnelasatri, Karnelasatri
0302079001
UNSPECIFIED
Uncontrolled Keywords: umbi bit merah (beta vulgaris l.); lip gloss; spf
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: University Subject > Current > Faculty/School - UPH Karawaci > Faculty of Health Sciences > Pharmacy (Diploma)
Current > Faculty/School - UPH Karawaci > Faculty of Health Sciences > Pharmacy (Diploma)
Depositing User: Aura Anastasya
Date Deposited: 04 Aug 2025 03:24
Last Modified: 04 Aug 2025 03:24
URI: http://repository.uph.edu/id/eprint/70277

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