Hubungan diabetes melitus tipe ii dengan kejadian osteoartritis pada pasien di Rumah Sakit Umum Siloam Lippo Village

Raphaela, Fellicia (2020) Hubungan diabetes melitus tipe ii dengan kejadian osteoartritis pada pasien di Rumah Sakit Umum Siloam Lippo Village. Bachelor thesis, Universitas Pelita Harapan.

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Abstract

Diabetes Melitus (DM) tipe II merupakan penyakit metabolik yang ditandai dengan meningkatnya glukosa dalam darah. Prevalensi diabetes menurut WHO tahun 2012 mencapai 422 juta orang. Pada diabetes melitus tipe II dapat terjadi komplikasi, salah satunya adalah osteoartritis (OA), karena adanya peningkatan produksi dari pro-inflammatory mediator yang menyebabkan peningkatan degradasi tulang rawan sehingga terjadi osteoartritis. Penelitian terdahulu menunjukan adanya hubungan antara DM tipe II selama lebih dari 10 tahun, pada usia diatas 50 tahun dengan kejadian osteoartritis dengan cara mengukur tingkat nyeri menggunakan kuesioner The Australian Canadian Osteoartritis Hand Index (AUSCAN) pain. Namun belum banyak dilaporkan hubungan antara DM tipe II yang diderita selama kurang dari 10 tahun, pada usia 50 - 60 tahun dengan kejadian osteoartritis yang diagnosa menggunakan American College Rheumatology (ACR). / Type II diabetes is a metabolic disease characterized by chronic hyperglycemia. The prevalence of people with diabetes type II according to WHO in 2012 reached 422 million people. Diabetes can cause complication, one of which is osteoartritis, because in diabetes melitus type II there is an increase in production from pro-inflammatory mediatros so that there is an increase in cartilage degradation process that causes osteoartritis. Published research reports that there is a relation between DM type II for more than 10 years, aged over 50 years with the incidencxe of osteoartritis by calculating the level pain using the AUSCAN questionnaire. However, there have not been many research between DM type II suffered in less than 10 years, at the age of 50-60 years with the incidence of osteoartritis diagnosed using American College Rheumatology (ACR).

Item Type: Thesis (Bachelor)
Creators:
CreatorsNIMEmail
Raphaela, FelliciaNIM01071170076felliciaraphaela@gmail.com
Contributors:
ContributionContributorsNIDN/NIDKEmail
Thesis advisorNalle, Trowce ListaUNSPECIFIEDUNSPECIFIED
Uncontrolled Keywords: osteoartritis; diabetes melitus tipe ii; acr
Subjects: R Medicine > R Medicine (General)
Divisions: University Subject > Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine
Current > Faculty/School - UPH Karawaci > Faculty of Medicine > Medicine
Depositing User: Fellicia Raphaela
Date Deposited: 19 Oct 2020 00:02
Last Modified: 21 Oct 2020 01:24
URI: http://repository.uph.edu/id/eprint/11383

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