Korelasi indeks massa tubuh dengan depresi pada pasien perempuan lupus eritematosus sistemik di Indonesia

Raissa, Sarah (2021) Korelasi indeks massa tubuh dengan depresi pada pasien perempuan lupus eritematosus sistemik di Indonesia. Bachelor thesis, Universitas Pelita Harapan.

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Abstract

Latar Belakang Salah satu penyebab depresi pada pasien LES diakibatkan oleh obesitas, terdapat dua faktor yaitu limitasi fungsionalitas dan efek samping dari terapi glukokortikoid. Obesitas pada pasien LES tentunya dapat meningkatkan faktor resiko seperti penyakit kardiovaskular dan diabetes. Oleh karena itu, bila obesitas pada pasien LES diatasi, maka dapat meningkatkan kesehatan pasien secara mental dan fisik. Tujuan Mengetahui apakah adanya korelasi antara tingkat IMT dengan depresi pada pasien perempuan LES. Metode Penelitian dilakukan menggunakan desain studi analitik korelasi. Sampel yang dibutuhkan sebanyak 27 pasien perempuan lupus eritematosus sistemik dan dipilih dengan teknik sampel acak sederhana. Hasil Pada penelitian ini terkumpul 30 sampel yang memenuhi kriteria inklusi. Mayoritas dari responden yang mengisi kuesioner, sebanyak 20 responden memiliki IMT normal dan hasil Beck Depression Inventory – II yang tergolong wajar. Metode Analisa Spearman mendapatkan hasil korelasi yang tidak signifikan antara IMT dan kejadian depresi pada pasien lupus eritematosus sistemik (p value = 0,297). Kesimpulan Tidak ditemukan hubungan signifikan antara IMT dan kejadian depresi pada pasien perempuan lupus eritematosus sistemik. Kata Kunci Lupus Eritematosus Sistemik (LES), IMT, Depresi / Introduction One of the causes of depression in SLE patients is obesity, there are two factors, namely limitation of functionality and side effects of glucocorticoid therapy. Obesity in SLE patients can certainly increase risk factors such as cardiovascular disease and diabetes. Therefore, if obesity in SLE patients is overcome, it can improve the patient's mental and physical health. Aim To determine whether there is a correlation between BMI levels and depression in female patients with SLE. Method This research was conducted using a correlation analytic study design. This research required 27 female patients with systemic lupus erythematosus and was selected using simple random sampling technique. Result In this study, 30 samples were collected that met the inclusion criteria. The majority of respondents who filled out the questionnaire, as many as 20 respondents had a normal BMI and the results of the Beck Depression Inventory – II were classified as reasonable. Spearman's analysis method obtained a non-significant correlation between BMI and the incidence of depression in patients with systemic lupus erythematosus (p value = 0.297). Conclusion There was no significant relationship between BMI and the incidence of depression in female patients with systemic lupus erythematosus. Keywords Systemic Lupus Erythematosus (SLE), BMI, Depression

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