Meaningful learning in class resulted in enduring understandings that the students will carry until they are adults and use in every aspect of their lives. The online setting made it harder for teachers to deliver meaningful learning and introduce God in the classroom because of teacher-student interaction limitations. At the same time, enduring understandings were still essential to be given based on the Truth. This paper aimed to explain how to conduct meaningful learning to result in the students' enduring understandings in an online setting from Christian epistemology point of view. The method used in this paper is a literature study with three focuses of study, which are enduring understanding, meaningful learning, and Christian epistemology. Enduring understandings would be remembered even when students forgot the details of the materials. Teachers should pay attention to factors that make an online learning process conducted meaningfully and lead students to find their enduring understandings revealed by the Lord. It needed teachers' willpower to practice and innovate the learning process and share with others.