Lingkungan pembelajaran klinis merupakan komponen penting dalam pendidikan keperawatan karena memungkinkan mahasiswa menerapkan teori ke dalam praktik langsung. Namun, hasil survei awal terhadap 14 mahasiswa profesi keperawatan menunjukkan masih ada yang belum siap kerja meskipun berada dalam lingkungan yang mendukung. Penelitian ini bertujuan mengetahui hubungan antara lingkungan pembelajaran klinis dengan kesiapan kerja mahasiswa profesi keperawatan. Penelitian menggunakan desain kuantitatif korelasional dengan pendekatan cross sectional. Sampel sebanyak 172 mahasiswa dipilih menggunakan teknik purposive sampling. Data dikumpulkan melalui kuesioner Clinical Learning Environment Diagnostic Inventory untuk mengukur lingkungan pembelajaran klinis dan Casey-Fink Readiness to Practice Survey untuk mengukur kesiapan kerja. Analisis dilakukan secara univariat dan bivariat. Hasil menunjukkan 167 (97.1%) mahasiswa menilai lingkungan pembelajaran klinis dalam kategori baik, dan 163 (94.8%) mahasiswa menyatakan siap untuk bekerja. Uji bivariat menunjukkan adanya hubungan signifikan antara lingkungan pembelajaran klinis dengan kesiapan kerja mahasiswa profesi keperawatan (p = 0,023). Hasil ini menegaskan bahwa lingkungan pembelajaran klinis yang baik berkontribusi terhadap kesiapan kerja, peneliti merekomendasikan penelitian lebih lanjut terhadap faktor lain yang memengaruhi kesiapan kerja. / The clinical learning environment is an important component of nursing education as it allows students to apply theory to hands-on practice. However, the results of an initial survey of 14 nursing profession students showed that there were still those who were not ready to work despite being in a supportive environment. This study aims to determine the relationship between clinical learning environment and work readiness of nursing profession students. The study used a correlational quantitative design with a cross sectional approach. A sample of 172 students was selected using purposive sampling technique. Data were collected through the Clinical Learning Environment Diagnostic Inventory questionnaire to measure the clinical learning environment and Casey-Fink Readiness to Practice Survey to measure work readiness. Univariate and bivariate analysis were conducted. Results showed 167 (97.1%) students rated the clinical learning environment in the good category, and 163 (94.8%) students stated they were ready to work. Bivariate test showed a significant relationship between clinical learning environment and work readiness of nursing profession students (p = 0.023). These results confirm that a good clinical learning environment contributes to work readiness, researchers recommend further research into other factors that affect work readiness.