Adaptasi kultural siswa Papua menunjukkan kebutuhan mendesak untuk pendekatan yang inklusif dan sensitif terhadap perbedaan budaya. Kesulitan komunikasi, kendala interaksi sosial, dan dampak psikologis pada siswa mengindikasikan perlunya pemahaman mendalam tentang dinamika adaptasi kultural agar sekolah dapat mendukung kesejahteraan psikologis dan hasil akademik siswa. Penelitian ini menggunakan pendekatan kualitatif untuk memahami secara mendalam proses adaptasi kultural yang terjadi antara siswa dan guru dari latar belakang budaya yang berbeda dan pendekatan Paradigma konstruktivis atau interpretif menekankan pada pemahaman mendalam tentang bagaimana individu dari budaya yang berbeda menafsirkan dan mengelola adaptasi kultural dalam lingkungan pendidikan atau beberapa sekolah berasrama yang memiliki keberagaman budaya antara siswa dan guru. Peneliti menemukan proses budaya mempengaruhi proses komunikasi dan interaksi di SLH Gunung Moria, akulturasi dan adaptasi komunikasi dihadapi oleh siswa Papua di SLH Gunung Moria umumnya memiliki kesamaan, yaitu berasal dari perbedaan budaya yang mencakup faktor bahasa, nilai-nilai, tradisi, dan pola komunikasi yang berbeda antara siswa dan guru. Kemudian proses tantangan utama yaitu ketidaksetaraan & kesenjangan. Kesenjangan geografis yang dihadapi siswa papua SLH Gunung Moria, seperti perbedaan iklim dan jarak dari keluarga serta sistem dukungan budaya, mempengaruhi proses adaptasi kultural mereka. Proses adaptasi kultural terhadap kesejahteraan psikologi & hasil akademik berupa dukungan sosial, kerohanian, sarana & prasarana. Pada siswa menghadapi hambatan terkait bahasa, nilai, dan pola budaya yang berbeda dengan guru mereka, serta hambatan semantik dalam penyampaian materi. Sarana dan Prasarana ini penting untuk dipertimbangkan dalam mendukung keberhasilan adaptasi kultural dan kesejahteraan psikologis siswa /The cultural adaptation of Papua students highlights the urgent need for an inclusive and culturally sensitive approach to address cultural differences. Communication difficulties, social interaction barriers, and the psychological impact on students indicate the necessity for a deeper understanding of cultural adaptation dynamics so that schools can support students' psychological well-being and academic outcomes. This study uses a qualitative approach to deeply understand the process of cultural adaptation that occurs between students and teachers from different cultural backgrounds, employing a constructivist or interpretivist paradigm that emphasizes a thorough understanding of how individuals from different cultures interpret and manage cultural adaptation in an educational setting or among boarding schools with cultural diversity between students and teachers. The researcher found that cultural processes affect communication and interaction at SLH Gunung Moria. The acculturation and communication adaptation faced by Papua students at SLH Gunung Moria generally have similarities, stemming from cultural differences, including language, values, traditions, and communication patterns between students and teachers. The main challenges identified include inequality and disparity. Geographical gaps faced by Papua students at SLH Gunung Moria, such as differences in climate, distance from their families, and cultural support systems, influence their cultural adaptation process. The process of cultural adaptation, which impacts psychological well-being and academic outcomes, involves social support, spirituality, and infrastructure. Students face barriers related to language, values, and cultural patterns that differ from those of their teachers, as well as semantic challenges in the delivery of educational material. Fasicilities and infrastructure are crucial considerations in supporting the success of cultural adaptation and the psychological well-being of students.